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抗 SREBP-1 兔抗
Anti-SREBP-1 antibody produced in rabbit
产品别名
抗 SREBP-1 兔抗
Anti-SREBP-1 antibody produced in rabbit
SREBF1
sterol regulatory element-binding protein 1
SREBP1
Sterol regulatory element-binding transcription factor 1
SRBP1
基本信息
| MDL number | MFCD02264110 |
| NACRES | NA.41 |
| General description【一般描述】 | Anti-SREBP-1 Antibody detects endogenous levels of total SREBP-1 protein. Sterol regulatory element binding protein-1 (SREBP1) is located on human chromosome 17p11.2. It belongs to the bHLH-Zip transcription factor family. SREBP-1 is a membrane-bound transcription factor liberated by sterol-regulated proteolysis.It is a 125 kD precursor that is bound to the nuclear envelope and endoplasmic reticulum. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human SREBP-1. Immunogen Range: 405-454 |
| Biochem/physiol Actions【生化/生理作用】 | Sterol regulatory element binding protein-1 (SREBP1) participates in the transcriptional regulation of cellular lipid homeostasis. It controls the hepatic gene expression of lipogenic enzymes and triglyceride deposition in the liver. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 121 kDa |
| species reactivity | rat, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P36956 |
| UniProt accession no.【UniProt登记号】 | P36956 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SREBF1(6720) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
