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Anti-Ribosomal Protein L26 (N-terminal) 兔抗
Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit
产品编号: | 3391785 |
规格: | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Ribosomal Protein L26 (N-terminal) 兔抗
Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit
Anti-RPL26
基本信息
MDL number | MFCD09265375 |
NACRES | NA.41 |
General description【一般描述】 | RPL26 (ribosomal protein L26) is located on chromosome 17. It codes for a 145-amino-acid long protein and has four exons. It is present on the large ribosomal subunit. Ribosomal protein L26 is one of the large ribosomal subunit proteins. |
Specificity【特异性】 | Anti-Ribosomal Protein L26 (N-terminal) specificallyrecognizes human Ribosomal Protein L26. |
Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 1-17 of human ribosomal protein L26, conjugated to KLH via a C-terminal added cysteine residue. The sequence is conserved in human, rat, and mouse. |
Application【应用】 | Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit has been used in:
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Biochem/physiol Actions【生化/生理作用】 | Ribosomal proteins are implicated in mRNA recognition, tRNA recognition and decoding and nuclear export. It was shown together with nucleolin to bind to the 5′ untranslated region of p53 mRNA and to control p53 translation and induction after DNA damage. RPL26 (ribosomal protein L26) regulates the expression of p73. It plays an important role in translation and stability of ribosomes. RPL26 frameshift mutation can cause several physical abnormalities. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 17 kDa |
species reactivity | human, mouse, rat |
concentration【浓度】 | ~1 mg/mL |
technique(s) | immunoprecipitation (IP): 5-10 μg using HEK-293T cell lysates indirect immunofluorescence: 5-10 μg/mL using paraformaldehye-fixed HeLa cells western blot: 0.5-1 μg/mL using HEK-293T cell extracts |
UniProt accession no.【UniProt登记号】 | P61254 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RPL26(6154) mouse ... Rpl26(19941) rat ... Rpl26(287417) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |