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Anti-phospho-APP (p668) antibody produced in rabbit
产品别名
Anti-phospho-APP (p668) antibody produced in rabbit
Anti-ABPP antibody produced in rabbit
Anti-AAA antibody produced in rabbit
Anti-amyloid beta (A4) precursor protein antibody produced in rabbit
Anti-ABETA antibody produced in rabbit
Anti-AD1 antibody produced in rabbit
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Peptide sequence around phosphorylation site of threonine 668 (A-V-T(p)-P-E), according to the protein APP. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 100-140 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (A-V-TP-P-E) |
NCBI accession no.【NCBI登记号】 | NP_000475.1 |
UniProt accession no.【UniProt登记号】 | P05067 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... APP(351) |
产品说明
Target description【目标描述】 | APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |