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Anti-PDGFR α antibody produced in rabbit
产品别名
Anti-PDGFR α antibody produced in rabbit
CD140a
kinase PDGFR-α
PDGF-R-α
PDGFR-α
α platelet-derived growth factor receptor precursor
基本信息
| MDL number | MFCD01322518 |
| NACRES | NA.41 |
| General description【一般描述】 | Platelet-derived growth factor receptor α (PDGFRA), also known as cluster of differentiation 140a (CD140a), is encoded by the gene mapped to human chromosome 4q12. The encoded protein belongs to the receptor tyrosine kinase gene family. Anti-PDGFR Anti-PDGFR α Antibody detects endogenous levels of total PDGFR α protein. Antibody detects endogenous levels of total PDGFR α protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human PDGFR alpha. Immunogen Range: 731-780 |
| Biochem/physiol Actions【生化/生理作用】 | Platelet-derived growth factor receptor plays a vital role in the development and maturation of platelets. Platelet-derived growth factor receptor α (PDGFRA) acts as a potential target for imatinib, a revolutionary drug for the treatment of chronic myeloid leukemia. PDGFRA pathway might be involved in developmental process of thrombocytes. The encoded protein facilitates hepatic stellate cell (HSCs) proliferation and migration. Mutation in the gene has been observed in gastrointestinal stromal tumors (GISTs). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 122 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | P16234 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PGFRA(5156) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
