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Anti-PBX2 (AB2) antibody produced in rabbit
产品别名
Anti-PBX2 (AB2) antibody produced in rabbit
Anti-G17
Anti-Pre-B-cell leukemia homeobox 2
Anti-PBX2MHC
Anti-HOX12
基本信息
NACRES | NA.41 |
General description【一般描述】 | PBX2 is a homeobox transcription factor that shares homology with the human proto-oncogene, PBX1. Studies have reported that PBX2 forms triple complexes with HOXA9 and MEIS1 in myeloid cells. Rabbit Anti-PBX2 (AB2) antibody recognizes pig, human, mouse, and rat PBX2. |
Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human PBX2 |
Application【应用】 | Rabbit Anti-PBX2 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml. |
Biochem/physiol Actions【生化/生理作用】 | PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. |
Sequence【序列】 | Synthetic peptide located within the following region: MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGK |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 46 kDa |
species reactivity | human, rat, horse, guinea pig, mouse |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_002577 |
UniProt accession no.【UniProt登记号】 | P40425 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PBX2(5089) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |