您的位置：首页 > 产品中心 > Anti-PAR4 antibody produced in rabbit
Anti-PAR4 antibody produced in rabbit
产品别名
Anti-PAR4 antibody produced in rabbit
Thrombin receptor-like 3
Proteinase-activated receptor 4
par-4
Coagulation factor II receptor-like 3
F2RL3
基本信息
| MDL number | MFCD02265744 |
| NACRES | NA.41 |
| General description【一般描述】 | F2R-like thrombin or trypsin receptor 3/coagulation factor 2 receptor-like 3 (F2RL3) gene codes for protease-activated receptor 4 (PAR4) protein. PAR4 belongs to the G protein-coupled receptors (GPCRs) family. It is expressed at high levels in the lungs, pancreas, thyroid, testis, and small intestine. PAR4 gene is located on human chromosome 19p12. Anti-PAR4 antibody detects endogenous levels of total PAR4 protein. Anti-PAR4 Antibody detects endogenous levels of total PAR4 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human PAR4. Immunogen Range: 29-78 |
| Application【应用】 | Anti-PAR4 antibody produced in rabbit has been used in immunoblotting (1:1000). |
| Biochem/physiol Actions【生化/生理作用】 | Protease-activated receptor 4 (PAR4) protein is involved in vascular inflammation. It is necessary for a stable thrombus as it mediates persistent thrombin signaling in platelets. PAR4 aids pro-inflammatory actions by interacting with the bradykinin B2 receptor. It is linked to renal function and the development of chronic kidney disease (CKD). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 41 kDa |
| species reactivity | rat, human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q96RI0 |
| UniProt accession no.【UniProt登记号】 | Q96RI0 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... F2RL3(9002) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
