Anti-PAK1 (Ab-212) antibody produced in rabbit

MFCD03457569

Peptide sequence around aa. 210-214 (P-V-T-P-T), according to the protein PAK1.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~68 kDa

mouse, human, rat

1 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

IgG

(P-V-T-P-T)

NP_001122092.1

Q13153

wet ice

−20℃

human ... PAK1(5058)

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

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10 - Combustible liquids

WGK 1