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Anti-MEF2A (Ab-312) antibody produced in rabbit
产品别名
Anti-MEF2A (Ab-312) antibody produced in rabbit
Anti-ADCAD1 antibody produced in rabbit
Anti-RSRFC9 antibody produced in rabbit
Anti-RSRFC4 antibody produced in rabbit
Anti-myocyte enhancer factor 2A antibody produced in rabbit
基本信息
NACRES | NA.41 |
General description【一般描述】 | MEF2A (myocyte enhancer factor 2A) belongs to the myocyte enhancer family of transcription factors. MEF2 codes for proteins, which helps to attach to a consensus CTA(T/A)4TAG/A sequence as homo- and heterodimers. It is mapped to chromosome 15q26. |
Immunogen【免疫原】 | Peptide sequence around aa. 310-314 (L-A-T-P-V), according to the protein MEF2A. |
Biochem/physiol Actions【生化/生理作用】 | MEF2A (myocyte enhancer factor 2A) mutation is associated with an autosomal dominant form of CAD (coronary artery disease). |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~54 kDa |
species reactivity | human, mouse, rat |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (L-A-T-P-V) |
NCBI accession no.【NCBI登记号】 | NP_001124398.1 |
UniProt accession no.【UniProt登记号】 | Q02078 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MEF2A(4205) |
产品说明
Target description【目标描述】 | The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |