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Anti-LIMD1 antibody produced in rabbit
产品别名
Anti-LIMD1 antibody produced in rabbit
Anti-LIM domains containing 1
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 56 kDa |
| species reactivity | guinea pig, rat, mouse, bovine, human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055055 |
| UniProt accession no.【UniProt登记号】 | Q9UGP4 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
基本信息
| General description【一般描述】 | LIMD1 codes for LIM domains containing 1 and is known to function as a tumor suppressor. It associates with pRB and inhibits transcription mediated by E2F. Rabbit Anti-LIMD1 antibody recognizes canine, human, mouse, and rat LIMD1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human LIMD1 |
| Application【应用】 | Rabbit Anti-LIMD1 antibody is suitable for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | LIMD1 may be involved in cell anchoring via focal adhesions and in the cell cycle, particularly during mitosis. LIMD1 functionally interacts with pRB and the loss of which promotes lung carcinogenesis. Some breast tumors also have altered expression of LIMD1 RNA. LIMD1 may represent a critical tumor suppressor gene. |
| Sequence【序列】 | Synthetic peptide located within the following region: MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFAT |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
