Anti-KLHL3, (N-terminal) antibody produced in rabbit

NA.41

Synthetic peptide directed towards the N terminal region of human KLHL3

KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Synthetic peptide located within the following region: CSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

65 kDa

bovine, horse, guinea pig, rat, human, mouse, rabbit

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NM_017415

Q9UH77

wet ice

−20℃

human ... KLHL3(26249)

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12 - Non Combustible Liquids

WGK 3