您的位置:首页 > 产品中心 > Anti-HOXC8 antibody produced in rabbit
Anti-HOXC8 antibody produced in rabbit
产品编号: | 3368324 |
规格: | ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-HOXC8 antibody produced in rabbit
Anti-Homeobox C8
Anti-Hox-3.1 (mouse)
Anti-HOX3A
Anti-Homeobox 3A
基本信息
NACRES | NA.41 |
General description【一般描述】 | Homeobox C8 (HOXC8) is a member of homeobox (HOX) family. It is a transcription factor, expressed in neural tube, brain, breast and adult bone marrow. HOX genes consist of a highly conserved 60-amino-acid region (the homeobox) with DNA-binding activity, that contributes to their activity as transcription factors. The gene is located on human chromosome 12q13. |
Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 96-110 of human HOXC8 conjugated to KLH. The corresponding sequence is identical in mouse and rat. |
Application【应用】 | Anti-HOXC8 antibody produced in rabbit has been used in immunoblotting and immunoprecipitation. |
Biochem/physiol Actions【生化/生理作用】 | Homeobox C8 (HOXC8) is involved in cell growth, migration and metastasis of various cancers. Hox genes are important for embryonic development. Mutations in this gene are implicated in the development of cancers, such as leukemias or neoplasms of the breast, prostate, kidney, colon, skin and brain. |
Physical form【外形】 | 0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。 |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~34 kDa |
species reactivity | human |
concentration【浓度】 | ~1.0 mg/mL |
technique(s) | immunoprecipitation (IP): 2.5-5 μg using lysates of HEK-293T cells over expressing human HOXC8 western blot: 1-2 μg/mL using extracts of HEK-293T cells over expressing human HOXC8 |
UniProt accession no.【UniProt登记号】 | P31273 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HOXC8(3224) mouse ... Hoxc8(15426) rat ... Hoxc8(24460) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |