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Anti-Growth Hormone Receptor antibody produced in goat
产品编号: | 3366254 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Growth Hormone Receptor antibody produced in goat
Anti-GHR
基本信息
MDL number | MFCD06201935 |
NACRES | NA.41 |
General description【一般描述】 | By immunoblotting, this antibody shows ~50% cross-reactivity with recombinant rat GHR and 20% cross-reactivty with recombinant human GHR. Growth Hormone Receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of intra- and intercellular signal transduction pathways. |
Immunogen【免疫原】 | purified, NSO-derived, recombinant mouse growth hormone receptor extracellular domain. |
Application【应用】 | Anti-Growth Hormone Receptor antibody produced in goat was used to study the protein and protein phosphorylation levels in rat primary hippocampal cultures using Li-cor Odyssey fluorescence technology. |
Biochem/physiol Actions【生化/生理作用】 | Growth hormone (GH) is secreted by the anterior pituitary and functions by binding specific growth hormone receptor (GHR). GH stimulates the secretion of insulin-like growth factor-1 that mediates some of its growth promoting actions. The activity of GH/GHR is important for normal physiology and aging processes. |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | mouse |
technique(s) | immunohistochemistry: 5-15 μg/mL using cells and tissues western blot: 0.1-0.2 μg/mL |
UniProt accession no.【UniProt登记号】 | P16882 |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Ghr(14600) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |