Anti-E2F1 antibody produced in rabbit

NA.41

E2F transcription factor 1 (E2F1), a member of the E2F family of transcription factors, is involved in the regulation of the cell cycle. E2F1 mediates cell proliferation and p53-dependent and independent apoptosis. E2F1 binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. The Rb/E2F1 axis exerts essential functions such as maintaining epidermal homoeostasis and suppressing tumour development in tissues such as the epidermis.

Rabbit polyclonal anti-E2F1 antibody reacts with human E2F transcription factor 1.

The immunogen for anti-E2F1 antibody: synthetic peptide derected towards the middle region of human E2F1

Rabbit polyclonal anti-E2F1 antibody is used to tag E2F transcription factor 1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of E2F transcription factor-1 in cell proliferation, apoptosis and tissue homeostasis.

Synthetic peptide located within the following region: LCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDP

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

IgG fraction of antiserum

100

primary antibodies

polyclonal

buffered aqueous solution

47 kDa

human

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NP_005216

Q01094

wet ice

−20℃

human ... E2F1(1869)

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12 - Non Combustible Liquids

WGK 3