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Anti-CCL17/TARC antibody produced in goat
| 产品编号： | 3351699 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Chemokine (C-C motif) ligand 17 (CCL17) belonging to the CC chemokine family. It is also known as thymus and activation regulated chemokine (TARC), ABCD-2, SCYA17, A-152E5.3. It is expressed constitutively in thymus and transiently in stimulated peripheral blood mononuclear cells. |
| Immunogen【免疫原】 | purified, E. coli-derived, recombinant human CCL-17. |
| Application【应用】 | Anti-CCL17/TARC antibody produced in goat is suitable for the following applications:
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| Biochem/physiol Actions【生化/生理作用】 | Thymus and activation regulated chemokine (TARC) may play an important role in T cell development as well as in trafficking and activation of mature T cells. It functions as a selective chemo-attractant for T cells that express a class of receptors binding TARC with high affinity and specificity. TARC acts as a functional ligand for CCR4, and CCR4 that are specific receptor for TARC selectively expressed on T cells. In Hodgkin lymphoma (HL) disease it is highly expressed and is a possible biomarker in HL patients. TARC expression is resistant to corticosteroid and is suppressed by PI3K enzyme inhibitors. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL neutralization: suitable western blot: 0.1-0.2 μg/mL |
| UniProt accession no.【UniProt登记号】 | Q92583 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CCL17(6361) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
