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抗 BAX 兔抗
Anti-Bax antibody produced in rabbit
产品别名
抗 BAX 兔抗
Anti-Bax antibody produced in rabbit
BCL2L4
Apoptosis regulator BAX
BAX
Bcl-2-like protein 4
Bcl2-L-4
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 21 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q07812 |
| UniProt accession no.【UniProt登记号】 | Q07812 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BAX(581) |
基本信息
| General description【一般描述】 | The BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) gene is mapped to human chromosome 19q13.33. It codes for α-helical globular protein. The protein contains eight amphipathic helices around a hydrophobic helix. Bax is known to be mostly localized in the cytoplasm. Anti-BAX antibody detects endogenous levels of total BAX protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Bax. Immunogen Range: 133-182 |
| Application【应用】 | Anti-BAX, C-Terminal antibody produced in rabbit has been used in western blotting analysis. |
| Biochem/physiol Actions【生化/生理作用】 | BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) is predominantly associated with cellular homeostasis, cell cycle and pathogenesis of cell death particularly in cancer cells. In response to an apoptotic stimulus, Bax brings about mitochondrial dysfunction and apoptosis. Oligomerization of bax promotes mitochondrial outer membrane permeabilization. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
