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Anti-Bax antibody produced in rabbit
| 产品编号： | 3347430 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Bax antibody produced in rabbit
Anti-BAX
基本信息
| MDL number | MFCD00282585 |
| NACRES | NA.41 |
| General description【一般描述】 | BCL2 associated X, apoptosis regulator (BAX) is a proapoptotic protein of the B-cell lymphoma 2 (BCL2) protein family. The gene encoding it is localized on human chromosome 19q13.33. |
| Immunogen【免疫原】 | Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax. |
| Application【应用】 | Anti-Bax antibody produced in rabbit has been used in Western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | BCL2 associated X, apoptosis regulator (BAX) forms a heterodimer with B-cell lymphoma 2 (BCL2) and functions as an apoptotic activator. BAX interacts with and increases the opening of the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in the mitochondrial membrane potential and the release of cytochrome c. The expression of BAX gene is regulated by the tumor suppressor p53 and BAX has been shown to be involved in p53-mediated apoptosis. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500343. |
| Physical form【外形】 | Supplied in PBS with 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | AAA03619 |
| UniProt accession no.【UniProt登记号】 | Q07812 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BAX(581) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
