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ANTI-BAT1(C-TERMINAL) antibody produced in rabbit
产品编号: | 3347408 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 400 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
ANTI-BAT1(C-TERMINAL) antibody produced in rabbit
56 kDa U2AF65-associated protein
BAT1
Spliceosome RNA helicase DDX39B
DDX39B
UAP56
基本信息
NACRES | NA.41 |
General description【一般描述】 | BAT1, also known as UAP56 or DExD-box helicase 39B (DDX39B), is encoded in the central region of the major histocompatibility complex (MHC) on the short arm of human chromosome 6p21.33. It is a member of DEAD box family of RNA-binding proteins and is characterized with the nine conserved motifs including ATPase and RNA helicase motifs. |
Application【应用】 | ANTI-BAT1(C-TERMINAL) antibody produced in rabbit has been used in immunoprecipitation and western blotting. |
Biochem/physiol Actions【生化/生理作用】 | BAT1/ UAP56 facilitates the binding of U2 small nuclear ribonucleoprotein (SnRP) to pre-mRNA. It also helps in the export of mRNA from the nucleus to the cytoplasm. Spliceosome RNA helicase BAT1 is implicated in adapting nucleic acid metabolism to cellular stress. BAT1 is implicated in the down-regulation of inflammation. The gene polymorphism might be associated with the development of allergic diseases such as bronchial asthma, allergic rhinitis, atopic dermatitis, food allergy, drug allergy and pollen allergy. Mutation in the gene may also lead to the development of urticaria and Quincke′s edema. |
Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 48991 Da |
species reactivity | human |
technique(s) | flow cytometry: 1:10-1:50 immunohistochemistry: 1:10-1:50 western blot: 1:1000 |
NCBI accession no.【NCBI登记号】 | NP_004631.1 |
UniProt accession no.【UniProt登记号】 | Q13838 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... DDX39B(7919) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |