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Anti-ATP7A antibody produced in chicken

产品编号:3346913
规格:affinity isolated antibody, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
334691350 μG4730
产品别名

Anti-ATP7A antibody produced in chicken

Anti-Copper-transporting ATPase 1

Anti-Menkes disease-associated protein

Anti-ATPase, Cu++ transporting, α polypeptide

基本信息
MDL number
MFCD03455449
NACRES
NA.41
Immunogen【免疫原】
Recombinant ATPase
Immunogen Sequence: GI # 4502321, sequence 1407-1500
Application【应用】
Anti-ATP7A antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions【生化/生理作用】
Copper-transporting ATPase 1 is a protein encoded by the ATP7A gene in humans. It mediates systemic copper absorption and provides cupro-enzymes in the trans-Golgi network (TGN) with copper. It constitutively cycles between the TGN and plasma membrane (PM) for regulating the metal homeostasis. Mutation in this gene causes Menkes disease, a rare X-linked recessive disorder characterized by multi-systemic disorder of copper deficiency. This disease is caused due to a novel "silent" substitution in the ATP7A gene.
Physical form【外形】
Solution in phosphate buffered saline containing 0.02% sodium azide.
产品性质
biological source【生物来源】
chicken
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
rat, human, mouse
manufacturer/tradename
Genway 15-288-21023
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_000043.1
UniProt accession no.【UniProt登记号】
Q04656
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ATP7A(538)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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