Anti-Atg101 antibody produced in rabbit

NA.41

Autophagy101 (Atg101) is located on the human chromosome at 12q13.13.

Anti-Atg101 antibody has been used in

• immunoblotting
• immunofluorescence
• immunopurification

Autophagy101 (Atg101) is a mammalian Autophagy13 (Atg13) binding protein essential for autophagy. Atg13 forms a stable complex with ULK1 (Serine/threonine-protein kinase ULK1) and FIP200 (FAK family kinase-interacting protein of 200 kDa). Atg101 associates with the ULK1-Atg13- FIP200 complex through direct interaction with Atg13. Mammalian target of rapamycin (mTOR) interacts with the ULK1-Atg13-FIP200 complex in a nutrient dependent manner, suggesting that mTOR regulates autophagy through this complex.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~30 kDa

human

~1.0 mg/mL

western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over expressing human Atg101

dry ice

−20℃

human ... C12orf44(60673)

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12 - Non Combustible Liquids