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8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer
产品别名
142754-27-6
8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer
Rp-8-Cl-cAMPS
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H10ClN5O5PSNa |
| Molecular weight | 401.70 |
| PubChem Substance ID【PubChem化学物质编号】 | 329774805 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Competitive inhibitor of cyclic AMP-dependent protein kinase A (PKA) type I. Membrane-permeable analog of the cAMP inhibitor Rp-cAMPS (Prod. No. A-165). |
| Features and Benefits【特点和优势】 | This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥99% (HPLC) |
| form【形式】 | solid |
| packaging【包装】 | vial of 5 μmol |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | Nc1ncnc2n([C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O)c(Cl)nc12 |
| InChI | 1S/C10H11ClN5O5PS/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14)/t3-,5-,6-,9-,22-/m1/s1 |
| InChI key | PJAHPRNGOHUYQD-KVBUDSETSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
