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6-硫-2′-脱氧鸟苷

6-Thio-2′-Deoxyguanosine
产品编号:3331446
规格:≥97% (HPLC)
CAS NO:789-61-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
33314465 MG1530
333144625 MG4490
产品别名

789-61-7

6-硫-2′-脱氧鸟苷

6-Thio-2′-Deoxyguanosine

2′-Deoxythioguanosine

NSC 71261

2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione (7CI,8CI)

2′-Deoxy-6-thioguanosine

2′-Ddeoxy-6-thio-guanosine

2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine

6-Thio-dG

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C10H13N5O3S
Molecular weight
283.31
PubChem Substance ID【PubChem化学物质编号】
329825770
NACRES
NA.77
Application【应用】
6-Thio-2′-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.
Biochem/physiol Actions【生化/生理作用】
6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥97% (HPLC)
form【形式】
powder
color【颜色】
white to brown
solubility【溶解性】
DMSO: 5 mg/mL, clear (warmed)
storage temp.【储存温度】
−20℃
SMILES string
S=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1
InChI
1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1
InChI key
SCVJRXQHFJXZFZ-HSUXUTPPSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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