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(R)-(+)-8-Hydroxy-DPAT hydrobromide

产品编号:3322286
规格:≥98% (HPLC), solid
CAS NO:78095-19-9
包装规格:5 MG,25 MG,100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
33222865 MG2060
332228625 MG5250
3322286100 MG17220
产品别名

78095-19-9

(R)-(+)-8-Hydroxy-DPAT hydrobromide

(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide

(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C16H25NO · HBr
Molecular weight
328.29
MDL number
MFCD00153810
PubChem Substance ID【PubChem化学物质编号】
24278480
NACRES
NA.77
Application【应用】
(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:
  • in mice to test the activity of the serotonin receptor
  • to test its effect on zebrafish melanocyte migration and survival
  • to stimulate hippocampal neurons

Biochem/physiol Actions【生化/生理作用】
(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.
(R)-(+)-8-Hydroxy-DPAT is a full 5-HT1A serotonin receptor agonist; active enantiomer of (±)-8-hydroxy-DPAT.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
solid
optical activity【旋光性】
[α]25/D +68.2°, c = 1 in methanol(lit.)
storage condition【储存条件】
protect from light
color【颜色】
white to off-white
solubility【溶解性】
H2O: >10 mg/mL at ±60 ℃ (with sonication)
SMILES string
Br.CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1
InChI
1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1
InChI key
BATPBOZTBNNDLN-PFEQFJNWSA-N
Gene Information
human ... HTR1A(3350)
packaging【包装】
5, 25, 100 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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