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Tetrabenazine
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3250213 | 10 MG | 2090 | |||
| 3250213 | 50 MG | 7050 |
产品别名
58-46-8
Tetrabenazine
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2H-benzo[a]quinolizin-2-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H27NO3 |
| Molecular weight | 317.42 |
| Beilstein | 40090 |
| EC number【EC 号】 | 200-383-6 |
| MDL number | MFCD08461052 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826731 |
| NACRES | NA.77 |
| Application【应用】 | Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. Tetrabenazine has also been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells2. |
| Biochem/physiol Actions【生化/生理作用】 | Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores. |
| Features and Benefits【特点和优势】 | This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Preparation Note【制备说明】 | Tetrabenazine is soluble in DMSO at a concentration that is greater than 10 mg/ml and is insoluble in water. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: >10 mg/mL H2O: insoluble |
| originator【创始人】 | Roche |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1cc2CCN3C[C@@H](CC(C)C)C(=O)CC3c2cc1OC |
| InChI | 1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1 |
| InChI key | MKJIEFSOBYUXJB-GDBMZVCRSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
