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RS-127445 hydrochloride
| 产品编号： | 3215871 |
| 规格： | ≥98% (HPLC), powder |
| CAS NO： | 199864-86-3 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3215871 | 5 MG | 1320 | |||
| 3215871 | 25 MG | 4860 |
产品别名
199864-86-3
RS-127445 hydrochloride
2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H16FN3 · HCl |
| Molecular weight | 317.79 |
| MDL number | MFCD11112196 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824019 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites. |
| Features and Benefits【特点和优势】 | This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥20 mg/mL |
| originator【创始人】 | Roche |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CC(C)c1cc(nc(N)n1)-c2ccc(F)c3ccccc23 |
| InChI | 1S/C17H16FN3.ClH/c1-10(2)15-9-16(21-17(19)20-15)13-7-8-14(18)12-6-4-3-5-11(12)13;/h3-10H,1-2H3,(H2,19,20,21);1H |
| InChI key | MKJPYBJBPRFMHL-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H315 - H319 - H335 |
| Precautionary Statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
