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Razoxane
产品别名
21416-67-1
Razoxane
ICRF 159
ICI 59118
NSC 129943
(±)-1,2-Bis(3,5-dioxopiperazinyl)propane
1,2-Bis(3,5-dioxo-1-piperazinyl)propane
Razoxin
4,4′-Propylenebis(2,6-piperazinedione)
(±)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
Tepirone
Troxozone
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H16N4O4 |
| Molecular weight | 268.27 |
| EC number【EC 号】 | 244-379-2 |
| MDL number | MFCD00430424 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824039 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Razoxane is clinically active against angiogenesis and metastasis. Razoxane specifically inhibits topoisomerase II without inducing DNA strand breaks (topo II catalytic inhibitor). It is an antimitotic agent with immunosuppressive properties. Razoxane inhibits blood-borne and lymphatic metastases in different experimental models. Studies have shown that razoxane inhibits specifically the vasculogenic mimicry of B16F10 melanoma cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >98% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: 40 mg/mL |
| storage temp.【储存温度】 | room temp |
| SMILES string | CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 |
| InChI | 1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19) |
| InChI key | BMKDZUISNHGIBY-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
