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Rabbit anti-Phospho 53BP1 (S25) Antibody, Affinity Purified
产品别名
Rabbit anti-Phospho 53BP1 (S25) Antibody, Affinity Purified
TP53
53BP1
p202
TDRD30
p53-binding protein 1
p53BP1
tumor protein p53-binding protein
1
tumor protein 53-binding protein
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Immunogen for PLA0126 was a phosphorylated synthetic peptide, which represented a portion of human p53 Binding Protein 1 (GeneID 7158) around serine 25 according to the numbering given in entry NP_005648.1. |
Physical form【外形】 | Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide |
Other Notes【其他说明】 | 53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
grade【等级】 | Powered by Bethyl Laboratories, Inc. |
species reactivity | mouse, human |
technique(s) | immunohistochemistry: 1:1,000- 1:5,000 immunoprecipitation (IP): 1- 4 μg/mg western blot: 1:2,000- 1:10,000 |
accession no.【登记号】 | NP_005648.1 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | human ... TP53BP1(7158) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |