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Rabbit anti-NONO Antibody, Affinity Purified
产品别名
Rabbit anti-NONO Antibody, Affinity Purified
NMT55
52 kDa subunit
55 kDa nuclear protein
protein phosphatase 1
p54(nrb)
54-kD
NonO protein
Nuclear RNA-binding protein
regulatory subunit 114
P54NRB
MRXS34
P54
NRB54
PPP1R114
non-Pou domain-containing octamer (ATGCAAAT) binding protein
DNA-binding p52/p100 complex
54 kDa nuclear RNA- and DNA-binding protein
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0119 maps to a region between residues 350 and 400 of human Non-POU Domain Containing, Octamer-binding using the numbering given in entry NP_031389.3 (GeneID 4841). |
| Physical form【外形】 | Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry: 1:200-1:1,000 immunoprecipitation (IP): 1- 4 μg/mg western blot: 1:2,000- 1:10,000 |
| accession no.【登记号】 | NP_031389.3 |
| UniProt accession no.【UniProt登记号】 | Q15233 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... NONO(4841) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
