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Pirenzepine dihydrochloride

产品编号:3182691
规格:≥98% (TLC), powder
CAS NO:29868-97-1
包装规格:500 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3182691500 MG1550
31826911 G2130
产品别名

29868-97-1

Pirenzepine dihydrochloride

5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H21N5O2 · 2HCl
Molecular weight
424.32
EC number【EC 号】
249-907-5
MDL number
MFCD00055214
PubChem Substance ID【PubChem化学物质编号】
24277863
NACRES
NA.77
General description【一般描述】
Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.
Application【应用】
Pirenzepine dihydrochloride has been used
  • in transactivation of fibroblast growth factor receptor (FGFR).
  • as a supplement in cell culture.
  • for the stimulation of human fibroblasts
Biochem/physiol Actions【生化/生理作用】
Selective M1 muscarinic acetylcholine receptor antagonist.
Features and Benefits【特点和优势】
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Caution【注意】
Hygroscopic; store desiccated at room temperature.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥98% (TLC)
form【形式】
powder
color【颜色】
white
solubility【溶解性】
H2O: 50 mg/mL
SMILES string
Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24
InChI
1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
InChI key
FFNMBRCFFADNAO-UHFFFAOYSA-N
Gene Information
human ... CHRM1(1128)
packaging【包装】
500 mg in poly bottle
1 g in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 2
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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