N-Butyldeoxynojirimycin

C₁₀H₂₁NO₄

219.28

MFCD00272581

24892070

NA.32

N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.

N-Butyldeoxynojirimycin has been used:

• in the inhibition of glycolipid synthesis in neuroblastoma cells
• in the inhibition the ceramide-specific glycosyltransferase in hepatocytes
• in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.

N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.
α-glucosidase Inhibitor

≥98% (TLC)

200

film (dried in situ)

water: 9.80-10.20 mg/mL, clear, colorless

2-8℃

CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1

UQRORFVVSGFNRO-UTINFBMNSA-N

human ... UGCG(7357)

1, 5 mg in glass bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)