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N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin
产品别名
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin
Ac-IEPD-AMC
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C32H41N5O11 |
Molecular weight | 671.69 |
MDL number | MFCD02259622 |
PubChem Substance ID【PubChem化学物质编号】 | 329770886 |
NACRES | NA.32 |
Amino Acid Sequence | NAc-Ile-Glu-Pro-Asp-AMC |
Substrates【底物】 | Fluorogenic substrate for caspase 8 and granzyme B. |
产品性质
Quality Level【质量水平】 | 200 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | powder |
solubility【溶解性】 | DMSO/DMF: 1 mg/mL |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2 |
InChI | 1S/C32H41N5O11/c1-5-16(2)28(33-18(4)38)31(46)35-21(10-11-25(39)40)32(47)37-12-6-7-23(37)30(45)36-22(15-26(41)42)29(44)34-19-8-9-20-17(3)13-27(43)48-24(20)14-19/h8-9,13-14,16,21-23,28H,5-7,10-12,15H2,1-4H3,(H,33,38)(H,34,44)(H,35,46)(H,36,45)(H,39,40)(H,41,42)/t16-,21-,22-,23-,28-/m0/s1 |
InChI key | XDMHHBKPMUGLEA-MNTOYCOOSA-N |
Gene Information | human ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002) mouse ... CFLAR(117279), GZMB(171528) rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |