Monoclonal Anti-CD48 antibody produced in mouse

NA.41

The antibody MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Cluster of differentiation 48 (CD48) molecule, also known as BLAST1, is encoded by the gene mapped to human chromosome 1q23.3. CD48 is a glycosyl-phosphatidyl-inositol (GPI)-anchored cell-surface protein of immunoglobulin superfamily. The encoded protein is expressed on various hematopoietic cells.

Raji human Burkitt′s lymphoma cell line

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Cluster of differentiation 48 (CD48) acts as an adhesion and co-stimulatory molecule and stimulates various effects in B and T lymphocytes, natural killer cells, mast cells and eosinophils. CD48 interacts with its ligand CD2 and other molecules and promotes rearrangement of signaling factors in lipid rafts, Lck-kinase activity and tyrosine phosphorylation.

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Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

MEM-102, monoclonal

buffered aqueous solution

human, nonhuman primates

1 mg/mL

flow cytometry: suitable

IgG1

NM_001778.2

P09326

wet ice

2-8℃

human ... CD48(962)

12 - Non Combustible Liquids