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Monoclonal Anti-ASNA1 antibody produced in mouse
| 产品编号： | 3141273 |
| 规格： | clone 2H3, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-ASNA1 antibody produced in mouse
Anti-ARSAI
Anti-MGC3821
Anti-ARSA1
Anti-arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | TMD recognition complex of 40 kDa (TRC40) also known as arsA arsenite transporter, ATP-binding, homolog 1 (ASNA1), is encoded by the gene mapped to human chromosome 19p13.2. ASNA1 is the mammalian ortholog of yeast Arr4/Get3 gene. The encoded protein is abundantly expressed in pancreatic β cells. ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, ArsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials. |
| Immunogen【免疫原】 | ASNA1 (NP_004308, 239 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence PEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ |
| Biochem/physiol Actions【生化/生理作用】 | Asna1/TRC40 interacts with the transmembrane domains (TMD) of newly released tail-anchored (TA) proteins and transfers them to the endoplasmic reticulum (ER) receptor for subsequent membrane insertion and thus, plays an essential role in TA protein biogenesis. The encoded protein is necessary for effective HSV1 replication. Asna1 acts as a key regulator of insulin signaling in C. elegans and mammalian cells. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 2H3, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable indirect ELISA: suitable indirect immunofluorescence: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 | IgG1κ |
| GenBank® accession no. | NM_004317 |
| UniProt accession no.【UniProt登记号】 | O43681 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ASNA1(439) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
