Monoclonal Anti-ACTB antibody produced in mouse

MFCD00164531

Actin β (ACTB) is encoded by the gene mapped to human chromosome 7p22.1. ACTB is a ubiquitously expressed cytoskeletal protein.

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. (provided by RefSeq)

ACTB (AAH01301, 1 a.a. ~ 375 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVSPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERRYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF

Monoclonal Anti-ACTB antibody produced in mouse has been used in western blots and immunohistochemistry.

Actin β (ACTB) is an endogenous housekeeping gene. It is extensively used as a reference gene/protein in quantifying expression levels in tumors. Mutation in the gene is associated with the development of Baraitser–Winter cerebrofrontofacial syndrome (BWCFF). Down regulated expression of the gene has been observed in liver, melanoma, renal, colorectal, gastric, pancreatic, esophageal, lung, breast, prostate, ovarian cancers, leukemia and lymphoma.

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Solution in phosphate buffered saline, pH 7.4

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100

mouse

unconjugated

purified immunoglobulin

primary antibodies

3G4-F9, monoclonal

buffered aqueous solution

mouse, human, rat

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

IgG1κ

BC001301

P60709

dry ice

−20℃

human ... ACTB(60)

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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)