您的位置:首页 > 产品中心 > 199106-13-3, MJ33 锂盐
MJ33 锂盐
MJ33 lithium salt
产品别名
199106-13-3
MJ33 锂盐
MJ33 lithium salt
1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol lithium
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C22H43F3O6PLi |
Molecular weight | 498.48 |
MDL number | MFCD03787978 |
PubChem Substance ID【PubChem化学物质编号】 | 24278549 |
NACRES | NA.77 |
Application【应用】 | MJ33 lithium salt has been used as a peroxiredoxin VI (Prdx6) inhibitor:
|
Biochem/physiol Actions【生化/生理作用】 | MJ33 acts as a non-toxic and potent inhibitor of agonist-induced activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase type 2 (NOX2). It also prevents lung injuries associated with lung inflammation in mice. MJ33 is a fluorinated lipid analog, which blocks the enzyme by mimicking the transition state of the substrate. Novel, active site directed, specific, competitive and reversible inhibitor of phospholipase A2 (PLA2). |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥90% (NMR) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | H2O: ≥5 mg/mL (warmed at 60 ℃) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCCCCCCCCCCCCCCCOCC(COCC(F)(F)F)OP(OC)([O-])=O.[Li+] |
InChI | 1S/C22H44F3O6P.Li/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-29-18-21(31-32(26,27)28-2)19-30-20-22(23,24)25;/h21H,3-20H2,1-2H3,(H,26,27);/q;+1/p-1 |
InChI key | GDLMLQJISATCEL-UHFFFAOYSA-M |
packaging【包装】 | 5 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |