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Gold nanoparticles
| 产品编号： | 3092050 |
| 规格： | 40 nm diameter, carboxylic acid functionalized, PEG 5000 coated, OD 50, dispersion in H2O |
| 包装规格： | 1 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Gold nanoparticles
Gold nanoparticles COOH functionalized
Gold Colloid
Au NP COOH
结构式
产品性质
| Quality Level【质量水平】 | 100 |
| material【物料】 | PEG 5000 |
| form【形式】 | dispersion in H2O nanoparticles |
| OD | 50 |
| Diameter【直径】 | 40 nm |
| pH【pH值(酸碱度)】 | 6.0-8.0 (25 ℃) |
| solubility【溶解性】 | water: miscible |
| density | 1.00 g/cm3 |
| λmax | 530 nm |
| functional group【官能团】 | carboxyl |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 1 mL in poly bottle |
基本信息
| General description【一般描述】 | Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields. They show excellent biocompatibility and attractive physicochemical properties. Poly (ethylene) glycol (PEG) surface coatings on gold nanoparticles help in the reduction of protein adsorption, reduce nonspecific interactions with cells and greatly improve the pharmokinetics of these nanoparticles and reduce aggregation of the nanoparticles. PEG layer density depends inversely on the AuNP curvature. Denser coating was possible on smaller AuNPs. Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between the negatively charged carboxylate groups and positively charged amino groups of protein. Since it adheres to cell membranes, it may find use in cellular and intracellular targeting in targeted drug delivery applications and also used in biodistribution studies. |
| Application【应用】 | Several other specific applications have been listed below:
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery. |
| Features and Benefits【特点和优势】 | The PEG coating decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
